USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: MUC18_HUMAN USC-OGP 2-DE database:  MUC18_HUMAN MUC18_HUMAN General information about the entry View entry in simple text format Entry name MUC18_HUMAN Primary accession number P43121 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Cell surface glycoprotein MUC18; AltName: Full=Cell surface glycoprotein P1H12; AltName: Full=Melanoma cell adhesion molecule; AltName: Full=Melanoma-associated antigen A32; AltName: Full=Melanoma-associated antigen MUC18; AltName: Full=S-endo 1 endothelial-associated antigen; AltName: CD_antigen=CD146; Flags: Precursor;. Gene name Name=MCAM Synonyms=MUC18 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1207: pI=6.04; Mw=38036 Cross-references UniProtKB/Swiss-Prot P43121; MUC18_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name MUC18_HUMAN Primary accession number P43121 Secondary accession number(s) O95812 Q59E86 Q6PHR3 Q6ZTR2 Sequence was last modified on  January 10, 2006 (version 2) Annotations were last modified on  March 15, 2017 (version 153) Name and origin of the protein Description RecName: Full=Cell surface glycoprotein MUC18; AltName: Full=Cell surface glycoprotein P1H12; AltName: Full=Melanoma cell adhesion molecule; AltName: Full=Melanoma-associated antigen A32; AltName: Full=Melanoma-associated antigen MUC18; AltName: Full=S-endo 1 endothelial-associated antigen; AltName: CD_antigen=CD146; Flags: Precursor; Gene name Name=MCAM Synonyms=MUC18 Encoded on Name=MCAM; Synonyms=MUC18 Keywords Alternative splicing; Cell adhesion; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Immunoglobulin domain; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M29277; AAA20824.1; -; mRNA EMBL M28882; AAA20922.1; -; mRNA EMBL X68264; CAA48332.1; -; Genomic_DNA EMBL X68265; CAA48332.1; JOINED; Genomic_DNA EMBL X68266; CAA48332.1; JOINED; Genomic_DNA EMBL X68267; CAA48332.1; JOINED; Genomic_DNA EMBL X68268; CAA48332.1; JOINED; Genomic_DNA EMBL X68270; CAA48332.1; JOINED; Genomic_DNA EMBL X68271; CAA48332.1; JOINED; Genomic_DNA EMBL AF089868; AAD17799.1; -; mRNA EMBL AK126303; BAC86520.1; -; mRNA EMBL AB209925; BAD93162.1; ALT_INIT; mRNA EMBL BC056418; AAH56418.1; -; mRNA CCDS CCDS31690.1; -. [P43121-1]; . PIR I38049; I38049; . RefSeq NP_006491.2; NM_006500.2. [P43121-1]; . UniGene Hs.599039; -; . ProteinModelPortal P43121; -; . BioGrid 110332; 13; . DIP DIP-52791N; -; . IntAct P43121; 5; . MINT MINT-1184800; -; . STRING 9606.ENSP00000264036; -; . iPTMnet P43121; -; . PhosphoSitePlus P43121; -; . SwissPalm P43121; -; . BioMuta MCAM; -; . DMDM 85681878; -; . EPD P43121; -; . MaxQB P43121; -; . PaxDb P43121; -; . PeptideAtlas P43121; -; . PRIDE P43121; -; . DNASU 4162; -; . Ensembl ENST00000264036; ENSP00000264036; ENSG00000076706. [P43121-1]; . GeneID 4162; -; . KEGG hsa:4162; -; . UCSC uc001pwf.4; human. [P43121-1]; . CTD 4162; -; . DisGeNET 4162; -; . GeneCards MCAM; -; . GeneCards MIR6756; -; . HGNC HGNC:6934; MCAM; . HPA CAB002147; -; . HPA HPA008848; -; . MIM 155735; gene; . neXtProt NX_P43121; -; . OpenTargets ENSG00000076706; -; . PharmGKB PA30678; -; . eggNOG ENOG410IEC2; Eukaryota; . eggNOG ENOG4110RPG; LUCA; . GeneTree ENSGT00530000063457; -; . HOGENOM HOG000015427; -; . HOVERGEN HBG002808; -; . InParanoid P43121; -; . KO K06534; -; . OMA PSRKSEF; -; . OrthoDB EOG091G072E; -; . PhylomeDB P43121; -; . TreeFam TF330534; -; . ChiTaRS MCAM; human; . GeneWiki CD146; -; . GenomeRNAi 4162; -; . PRO PR:P43121; -; . Proteomes UP000005640; Chromosome 11; . Bgee ENSG00000076706; -; . CleanEx HS_MCAM; -; . ExpressionAtlas P43121; baseline and differential; . Genevisible P43121; HS; . GO GO:0009897; C:external side of plasma membrane; IDA:UniProtKB; . GO GO:0005615; C:extracellular space; IEA:Ensembl; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW; . GO GO:0005634; C:nucleus; IEA:Ensembl; . GO GO:0005886; C:plasma membrane; NAS:ProtInc; . GO GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc; . GO GO:0001525; P:angiogenesis; IDA:MGI; . GO GO:0007155; P:cell adhesion; TAS:ProtInc; . GO GO:0003094; P:glomerular filtration; IEP:UniProtKB; . GO GO:0030335; P:positive regulation of cell migration; IEA:Ensembl; . GO GO:0061042; P:vascular wound healing; IEP:UniProtKB; . Gene3D 2.60.40.10; -; 5; . InterPro IPR013162; CD80_C2-set; . InterPro IPR007110; Ig-like_dom; . InterPro IPR013783; Ig-like_fold; . InterPro IPR003599; Ig_sub; . InterPro IPR003598; Ig_sub2; . InterPro IPR013106; Ig_V-set; . InterPro IPR013151; Immunoglobulin; . Pfam PF08205; C2-set_2; 1; . Pfam PF00047; ig; 1; . Pfam PF07686; V-set; 1; . SMART SM00409; IG; 5; . SMART SM00408; IGc2; 3; . SUPFAM SSF48726; SSF48726; 5; . PROSITE PS50835; IG_LIKE; 5; .

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